Ketoconazole and Zinc Pyrithione Shampoo- This shampoo is a kind of medication that is used for treating certain skin condition. There is a fungus that is responsible for many problems related to dandruff and it also infects the skin or scalp, resulting in dry, flaky skin (scales) on the scalp, face, ears, chest, or upper back. This shampoo is very effective in solving this kind of problem. This shampoo has anti-fungal affects that helps in increase the permeability of fungal cell membrane by inhibiting the ergosterol synthesis.

This medication work by inhibiting formation of ergosterol in fungus which increases the fluidity in membrane and stop the fungus growth. This shampoo is formulated by using two different types of chemical composition and these both are different properties that helps in solving scalp problem due to fungus infection. One compound inhibits the cell membrane formation and there one has properties like fungistatic and bacteriostatic properties which helps in treating skin related problems caused by these organisms.

Indication for using Ketoconazole and Zinc Pyrithione Shampoo

As we have mentioned this is a chemical-based shampoo that solves many problems related to fungal infection on the scalp and this must be used when you observe these symptoms that are mentioned below.

• Seborrheic dermatitis
• Dandruff due to fungal infection
• Histoplasmosis
• Recalcitrant Dermophytosis

Mechanisms of Ketoconazole and Zinc Pyrithione Shampoo

This chemical-based shampoo solves dandruff problem cause by the fungal infections and this shampoo is formulated by using two different composition which tackles the fungal infection in different ways based in their properties and their mode of actions are mentioned below.

Ketoconazole- This chemical composition has antifungal properties that helps in stopping the duplication process of the fungus by stopping the fungus’s cell growth and stops it from spreading throughout the scalp.

Zinc Pyrithione- Metabolisms is an important process for every organism and Zinc Pyrithione inhibits the metabolisms process in microbial organisms because this composition decreases the Fe-S protein in the microorganism.

Side Effects of Ketoconazole and Zinc Pyrithione Shampoo

This shampoo is chemical based formation which mean it can react with other enzymes or chemical that are available on the skin that may cause some of the side effects normally this shampoo has no side effects but sensitive skin may suffer form these side effects due to the use of this shampoo.

• Dry Skin
• Rash or redness in the scalp
• Effects on the hair texture
• Scalp pustules

Chemical Interaction for Ketoconazole and Zinc Pyrithione Shampoo

If you are using this compound avoid using these compound that are mentioned below because this chemical may interact with these compounds and can cause some unnecessary reactions.

• Adapalene
• Alitretinoin
• Tazarotene
• Tretinoin

Way to Use Ketoconazole and Zinc Pyrithione Shampoo

Medication has a right way to use, this shampoo has one too. These are some of the instructions by following that you can get good result from this shampoo.

1. First wet your hair and scalp with water.
2. Then apply the Shampoo most at the affected area.
3. Massage your scalp make good lather.
4. Let it be at least for 5-6 min.
5. At last clean your hair and scalp with moderate warm water that you can handle and then dry your hair.